Comparison of IV salbutamol with IV aminophylline in the treatment of severe, acute asthma in childhood.
نویسندگان
چکیده
A double-blind test to compare IV aminophylline with salbutamol in the treatment of acute, uncontrolled asthma showed that both drugs were equally effective during the first 24 hours. Salbutamol caused a relative tachycardia. Hydrocortisone was given after 2 hours, but did not appear to affect the rate of recovery.
منابع مشابه
Comparison of IV salbutamol with IV aminophylline in severe acute asthma.
Correspondence Comparison of IV salbutamol with IV aminophylline in severe acute asthma Sir, In a double-blind comparative study of children with acute asthma, Hambleton and Stone (Archives, 1979, 54, 391) showed that IV salbutamol and aminophylline were equally effective when given during the first 24 hours. The optimal use of theophylline requires a dosage regimen that maintains the serum con...
متن کاملRandomised controlled trial of aminophylline for severe acute asthma.
OBJECTIVES To determine whether children with severe acute asthma treated with large doses of inhaled salbutamol, inhaled ipratropium, and intravenous steroids are conferred any further benefits by the addition of aminophylline given intravenously. STUDY DESIGN Randomised, double blind, placebo controlled trial of 163 children admitted to hospital with asthma who were unresponsive to nebulise...
متن کاملIntravenous salbutamol bolus compared with an aminophylline infusion in children with severe asthma: a randomised controlled trial.
BACKGROUND The relative efficacies of aminophylline and salbutamol in severe acute childhood asthma are currently unclear. A single bolus of salbutamol was compared with a continuous aminophylline infusion in children with severe asthma in a randomised double blind study. METHODS Children aged 1-16 years with acute severe asthma were enrolled if they showed little improvement with three nebul...
متن کاملEffect of adding aminophylline infusion to nebulised salbutamol in severe acute asthma.
BACKGROUND The benefit of adding theophylline to beta 2 agonists in acute asthmatic attacks has been debated frequently. METHODS In an open randomised study 25 patients with severe acute asthma who presented to the emergency department were treated with either a combined nebulised salbutamol (5 mg/dose) and aminophylline infusion (0.6-0.9 mg/kg/hour), or nebulised salbutamol alone. RESULTS ...
متن کاملCardiovascular response during severe acute asthma and its treatment in children.
Heart rate, blood pressure, pulsus paradoxus, and cardiac output measured by means of transthoracic electrical impedance cardiography have been recorded in 29 children mean age 10 years +/- 2 SD during status asthmaticus. Changes were recorded over the first two hours of treatment during which all patients received oxygen, intravenous fluid, and hydrocortisone, and were randomly assigned to rec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Archives of disease in childhood
دوره 54 5 شماره
صفحات -
تاریخ انتشار 1979